Presentation Title: FPA150: A recombinant, afucosylated,
fully human IgG1 monoclonal antibody for the treatment of malignancies
that express high levels of B7-H4
Presenter Name: Charles D. Kaplan
Session Type: Drug Development Track - Special Session
Session Title: New Drugs on the Horizon 1
Session Start Time:
Location: Room S103 -
FPA150 is a novel, fully human, afucosylated monoclonal antibody targeting B7-H4. B7-H4 expression is observed in multiple solid tumors, including breast, bladder and gynecologic cancers, and has been documented to correlate with poor prognosis. FPA150 is designed with a dual mechanism of action: blocking the T cell checkpoint activity of B7-H4 as well as delivering potent antibody-dependent cell-mediated cytotoxicity against tumor cells expressing B7-H4. Five Prime anticipates initiating Phase 1 development of FPA150 during the first half of 2018.
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Five Prime Therapeutics, Inc.
Heather Rowe, 415-365-5737
Senior Director, Investor Relations and Corporate Communications